Average Treatment Duration
45-90 minutes (including blood draw and prep)
Average Downtime After Treatment
Minimal to none
Average Treatments Needed
Reported Discomfort Level
Mild swelling or bruising may occur
Expected Price Range
Results
Gradual; improvements typically seen within 1–3 months
PRF/ezGEL is an advanced, all-natural injectable treatment that harnesses your body’s own regenerative power to restore facial volume, improve skin texture and tone, and stimulate long-term collagen and elastin production.

This next-generation treatment combines Platelet-Rich Fibrin (PRF) with heat-treated plasma proteins—specifically serum albumin—to create a gel-like matrix rich in platelets, leukocytes, stem cells, and growth factors. Unlike traditional fillers, PRF/ezGEL is completely autologous (derived from your own blood), making it a safe and powerful alternative to synthetic injectables.

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How PRF/ezGEL Works

  1. Blood Collection
    A small amount of your blood is drawn in-office.
  2. Centrifugation
    The blood is spun in a low-speed centrifuge to isolate PRF—concentrating platelets, white blood cells, and stem cells—without the use of anticoagulants or additives.
  3. Thermal Processing
    Portions of the plasma are gently heated and cooled to create a viscous, gel-like substance from albumin proteins.
  4. Combination
    The PRF is mixed with the albumin gel to form PRF/ezGEL—an injectable that both volumizes and releases growth factors gradually over 7–10 days for sustained rejuvenation.
  5. Treatment Plan
    A series of treatments spaced over several weeks is typically recommended for optimal, lasting results.

Key Difference from PFP

PRF releases growth factors more slowly and over a longer period (up to 7–10 days), providing a more sustained healing and rejuvenation effect.

Aesthetic Uses

  • Under-eye rejuvenation (dark circles, hollowing)
  • Lip and facial volume enhancement
  • Fine lines and wrinkles
  • Uneven tone and poor texture
  • Skin laxity and collagen loss
  • Hair restoration (scalp injections)

Benefits of PRF/ezGEL

  • 100% Natural – No synthetic ingredients, just your body’s own healing components
  • Immediate + Ongoing Results – Volumizes instantly while stimulating long-term collagen production
  • Versatile – Effective across multiple facial areas including cheeks, lips, jawline, and under-eyes
  • Minimal Downtime – Most patients experience little to no recovery time
  • Safe and Biocompatible – No risk of allergic reactions or synthetic filler complications
  • Long-Lasting – Results continue to improve over 1–3 months and can last several months
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Dr. LaBine consulting with a patient in a treatment room, highlighting personalized skincare planning and attentive dermatologic care.